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Alfadoxin (Brand name: Cardura) Online

  • €0,26
  • Brand name: Cardura
  • Verfügbarkeit: Lagernd
  • Wirkstoff: Doxazosin
Alfadoxin wird zur Behandlung von Bluthochdruck oder Zeichen und Symptomen der benignen Prostatahyperplasie (BPH) verwendet.
Analog zu Alfadoxin (Brand name: Cardura): Doxazosin  
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Andere Namen von Alfadoxin (Brand name: Cardura): a   b   c   d   e   f   g   h   i   j   k   l   m   n   o   p   q   r   s   t   u   v   w   x   y   z  
Atensil   Ascalan   Artezine   Apo-doxan   Alphapres   Alflosin   Alfamedin   Alfadoxin   Alfadil   Alfadox   Alfazosin   Alphapres   Apo-doxan   Alfadil   Alfadil BPH   Alfadoxin   Angicon   Apo-Doxazosin   Ascalan   Alfadoxin  
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4 mg
Produktname Pro Pille Pro Packung  
30 pillen €1,40 €42,04
60 pillen €1,11 €84,08 €66,65
90 pillen €1,01 €126,13 €91,27
120 pillen €0,97 €168,17 €115,88
180 pillen €0,92 €252,25 €165,11
270 pillen €0,88 €378,38 €238,94
360 pillen €0,87 €504,50 €312,80
2 mg
Produktname Pro Pille Pro Packung  
30 pillen €1,08 €32,32
60 pillen €0,85 €64,64 €51,24
90 pillen €0,78 €96,96 €70,16
120 pillen €0,74 €129,28 €89,08
180 pillen €0,71 €193,91 €126,93
270 pillen €0,68 €290,87 €183,68
360 pillen €0,67 €387,83 €240,44
1 mg
Produktname Pro Pille Pro Packung  
90 pillen €0,39 €35,44
180 pillen €0,30 €70,88 €54,34
270 pillen €0,27 €106,31 €73,24
360 pillen €0,26 €141,75 €92,14

INDICATIONS

Alfadoxin is used for treating high blood pressure and treating signs and symptoms of benign prostatic hyperplasia (BPH). Alfadoxin is an alpha-blocker. It works by relaxing muscles in the blood vessels, resulting in lowering of blood pressure. In men with BPH, alpha-blockers work by relaxing muscles around the urethra (the tube that drains urine from the bladder), which improves urinary symptoms.

INSTRUCTIONS 

Use Alfadoxin as directed by your doctor.

  • Take Alfadoxin by mouth with or without food.
  • Alfadoxin may cause a sudden drop in blood pressure after the first dose. Take your first dose at bedtime. If you get up during the night, sit up slowly, then stand slowly.
  • If you miss a dose of Alfadoxin, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Alfadoxin.

STORAGE

Store Alfadoxin at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Alfadoxin out of reach of children and away from pets.

MORE INFO:

Active Ingredient: Doxazosin mesylate.

SAFETY INFORMATION

Do NOT use Alfadoxin if:

  • you are allergic to any ingredient of Alfadoxin or to similar medicines (eg, prazosin).

Some medical conditions may interact with Alfadoxin. Tell your health care provider if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a history of prostate cancer, kidney or liver problems, or high or low blood pressure
  • if you will be having eye surgery.

Some medicines may interact with Alfadoxin. Tell your health care provider if you are taking any other medicines, especially any of the following.

  • Phosphodiesterase type 5 inhibitors (eg, sildenafil, vardenafil) because severe low blood pressure may occur
  • Clarithromycin, HIV protease inhibitors (eg, ritonavir), itraconazole, ketoconazole, nefazodone, telithromycin, or voriconazole because they may increase the risk of Alfadoxin's side effects.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Alfadoxin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Important safety information:

  • Alfadoxin may cause drowsiness, dizziness, lightheadedness, or fainting. These effects may be worse if you take it with alcohol or certain medicines. Use Alfadoxin with caution. Do not drive or perform other possible unsafe tasks until you know how you react to it.
  • Alfadoxin may cause a sudden drop in blood pressure after the first dose. Take your first dose at bedtime. If you get up during the night, sit up slowly, then stand slowly. This will help to reduce your lightheadedness or dizziness. These effects will more likely occur after the first few doses or if your dose has increased, but can occur at any time while you are taking the medicine. It can also occur if you stop taking the medicine and then restart treatment.
  • Alfadoxin may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
  • Do NOT take more than the recommended dose without checking with your doctor.
  • Tell your doctor or dentist that you take Alfadoxin before you receive any medical or dental care, emergency care, or surgery (including eye surgery).
  • Alfadoxin may rarely cause a prolonged, painful erection. This could happen even when you are not having sex. If this is not treated right away, it could lead to permanent sexual problems such as impotence. Contact your doctor right away if this happens.
  • Patients who take medicine for high blood pressure often feel tired or run down for a few weeks after starting treatment. Be sure to take your medicine even if you may not feel 'normal.' Tell your doctor if you develop any new symptoms.
  • Lab tests, including blood pressure, may be performed while you use Alfadoxin. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Use Alfadoxin with caution in the elderly; they may be more sensitive to its effects, especially low blood pressure.
  • Alfadoxin should not be used in children; safety and effectiveness in children have not been confirmed.
  • Pregnancy and breast-feeding: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Alfadoxin while you are pregnant. It is not known if Alfadoxin is found in breast milk. If you are or will be breast-feeding while you use Alfadoxin, check with your doctor. Discuss any possible risks to your baby.

SIDE EFFECTS

All medicines may cause side effects, but many people have no, or minor, side effects.

Check with your doctor if any of these most common side effects persist or become bothersome:

Dizziness; drowsiness; lightheadedness; nasal congestion; tiredness; weakness.

Seek medical attention right away if any of these severe side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; fainting; irregular heartbeat; prolonged, painful erection; severe or prolonged dizziness or headache; shortness of breath; swelling of the ankles, feet, or hands; vision changes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.

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Es ist wichtig, den Sicherheitsempfehlungen zu folgen und die Gegenanzeigen, Warnhinweise und Vorsichtsmaßnahmen zu berücksichtigen, damit sich das Risiko schlimmer Reaktionen und Nebenwirkungen reduziert. Es kommt leider bei Patienten mit Überempfindlichkeit gegen einigen Komponenten des Arzneimittels zu leichten bis schweren nachteiligen Reaktionen, die im Text unten zu finden sind. Um das Risiko ernster Folgen auszuschalten, wenden Sie sich an Ihren Therapeuten oder an einen Online-Facharzt. Man benötigt dringende medizinische Hilfe, wenn folgende Nebenwirkungen zu bemerken sind:

Rare

  • Painful or prolonged erection of the penis (called priapism), although extremely rare, must have immediate medical attention. If painful or prolonged erection occurs, call your doctor or go to an emergency room as soon as possible

More Common

  • Dizziness or lightheadedness
  • Headache
  • lack or loss of strength
  • unusual tiredness or weakness

Less Common

  • Blurred vision
  • confusion
  • dizziness, faintness, or lightheadedness when getting up from a lying or sitting position
  • fainting (sudden)
  • fast and pounding heartbeat
  • irregular heartbeat
  • shortness of breath
  • sweating
  • swelling of feet or lower legs
  • Acid or sour stomach
  • back pain
  • belching
  • bladder pain
  • cloudy urine
  • difficulty in moving
  • frequent urge to urinate
  • heartburn
  • indigestion
  • joint pain
  • lower back or side pain
  • muscle aching, cramping, or weakness
  • muscle pains or stiffness
  • nausea
  • nervousness, restlessness, unusual irritability
  • runny nose
  • sleepiness or drowsiness
  • sneezing
  • sore throat
  • stomach discomfort, upset or pain
  • swollen joints

Incidence Not Known

  • Abdominal or stomach pain
  • area rash
  • black, tarry stools
  • bleeding gums
  • blood in urine or stools
  • chest pain or discomfort
  • chills
  • clay-colored stools
  • cough
  • dark urine
  • diarrhea
  • difficulty breathing
  • difficult, burning, or painful urination
  • fever
  • general tiredness and weakness
  • headache, sudden and severe
  • inability to speak
  • itching
  • lab results that show problems with liver
  • light-colored stools
  • loss of appetite
  • noisy breathing
  • pain or discomfort in arms, jaw, back or neck
  • pinpoint red or purple spots on skin
  • rash
  • seizures
  • slow or irregular heartbeat
  • slurred speech
  • sore throat
  • sores, ulcers, or white spots on lips or in mouth
  • swollen glands
  • temporary blindness
  • tightness in chest
  • unpleasant breath odor
  • unusual bleeding or bruising
  • upper right abdominal pain
  • vomiting
  • vomiting of blood
  • weakness in arm and/or leg on one side of the body, sudden and severe
  • wheezing
  • yellow eyes and skin
  • Anxiety
  • burning, crawling, itching, numbness, prickling, “pins and needles”, or tingling feeling
  • change in frequency or urination
  • dry mouth
  • feeling of warmth
  • frequent urination
  • general feeling of discomfort or illness
  • hair loss
  • hives or welts
  • hyperventilation
  • increased urge to urinate during the night
  • increased volume of pale dilute urine
  • loss of appetite
  • painful urination
  • redness of skin
  • redness of the face, neck, arms and occasionally upper chest
  • shaking
  • swelling of the breasts or breast soreness in both females and males
  • thinning of hair
  • trouble in holding or releasing urine
  • trouble sleeping
  • waking to urinate at night
  • weight loss
Type Small Molecule
Accession Number DB00590  (APRD00474)
Groups Approved
Synonyms
  • 1-(4-Amino-6,7-dimethoxy-2-chinazolinyl)-4-(2,3-dihydro-1,4-benzodioxixin-2-ylcarbonyl)piperazin
  • 1-(4-Amino-6,7-Dimethoxy-2-quinazolinyl)-4-(1,4-benzodioxan-2-ylcarbonyl)piperazin
  • Doxazosina
  • Doxazosine
  • Doxazosinum
UNII NW1291F1W8
CAS number 74191-85-8
Weight Average: 451.4751
Monoisotopic: 451.185568935
Chemical Formula C23H25N5O5
InChI
InChI=1S/C23H25N5O5/c1-30-18-11-14-15(12-19(18)31-2)25-23(26-21(14)24)28-9-7-27(8-10-28)22(29)20-13-32-16-5-3-4-6-17(16)33-20/h3-6,11-12,20H,7-10,13H2,1-2H3,(H2,24,25,26)
IUPAC Name
2-[4-(2,3-dihydro-1,4-benzodioxine-2-carbonyl)piperazin-1-yl]-6,7-dimethoxyquinazolin-4-amine
Protein binding

98%

Toxicity

Symptoms of overdose include hypotension. Oral LD50 is greater than 1000 mg/kg in mice and rats.

Half life

22 hours

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