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Alfuzosinehydrochloride retard PCH (Brand name: Uroxatral) Online

  • €1,29
  • Brand name: Uroxatral
  • Verfügbarkeit: Lagernd
  • Wirkstoff: Alfuzosin
Alfuzosinehydrochloride retard PCH (Alfusozin) wird zur Behandlung von Symptomen von benigner Prostatahyperplasie (BHP) bei Patienten mit einer vergrößten Prostata angewendet.
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Alle anzeigen

10 mg
Produktname Pro Pille Pro Packung  
30 pillen €1,80 €53,87
60 pillen €1,52 €107,73 €91,28
90 pillen €1,43 €161,60 €128,69
120 pillen €1,38 €215,46 €166,10
180 pillen €1,34 €323,19 €240,93
270 pillen €1,31 €484,79 €353,17
360 pillen €1,29 €646,38 €465,38

INDICATIONS

Alfuzosinehydrochloride retard PCH is used for treating symptoms of benign prostatic hyperplasia (BPH) in men with an enlarged prostate. It may also be used for certain conditions as determined by your doctor.

Alfuzosinehydrochloride retard PCH (alfuzosin) belongs to a group of drugs called alpha-adrenergic blockers. Alfuzosinehydrochloride retard PCH relaxes the muscles in the prostate and bladder neck, making it easier to urinate.

Alfuzosinehydrochloride retard PCH may also be used for other purposes not listed in this medication guide.

INSTRUCTIONS 

Take Alfuzosinehydrochloride retard PCH exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Your doctor may occasionally change your dose to make sure you get the best results.

Alfuzosinehydrochloride retard PCH is usually taken once a day, just after a meal. Try to take this medication at the same time each day. Do not take it on an empty stomach. Do not crush, chew, or break an extended-release tablet. Swallow it whole. Breaking the pill may cause too much of the drug to be released at one time. Alfuzosinehydrochloride retard PCH lowers blood pressure and may cause dizziness or fainting, especially when you first start taking it, or when you start taking it again. Call your doctor if you have severe dizziness or feel like you might pass out.

If you missed a dose take it as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

DOSAGE 

Use the medicine as prescribed by your doctor.

STORAGE 

Store Alfuzosinehydrochloride retard PCH at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Keep Alfuzosinehydrochloride retard PCH out of the reach of children and away from pets.

MORE INFO:

Active Ingredient: Alfuzosin

SAFETY INFORMATION

You should not use Alfuzosinehydrochloride retard PCH if you are allergic to alfuzosin, if you have severe liver disease, or if you are also using ketoconazole (Nizoral), itraconazole (Sporanox), or ritonavir (Norvir). Do not take Alfuzosinehydrochloride retard PCH with other similar medicines such as doxazosin (Cardura), prazosin (Minipress), silodosin (Rapaflo), tamsulosin (Flomax), or terazosin (Hytrin).

Alfuzosinehydrochloride retard PCH may cause dizziness or fainting. Be careful if you drive or do anything that requires you to be alert. Avoid standing for long periods of time or becoming overheated during exercise and in hot weather. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.

Alfuzosinehydrochloride retard PCH can affect your pupils during cataract surgery. Tell your eye surgeon ahead of time that you are using this medication. Do not stop using Alfuzosinehydrochloride retard PCH before surgery unless your surgeon tells you to.

There are many other drugs that can interact with Alfuzosinehydrochloride retard PCH. Tell your doctor about all medications you use.
Before taking Alfuzosinehydrochloride retard PCH

Do not use Alfuzosinehydrochloride retard PCH if you are allergic to alfuzosin, or if you have:

severe liver disease;

if you are also taking similar medicines such as doxazosin (Cardura), prazosin (Minipress), silodosin (Rapaflo), tamsulosin (Flomax), or terazosin (Hytrin); or

if you are also using ketoconazole (Nizoral), itraconazole (Sporanox), or ritonavir (Norvir).

If you have any of these other conditions, you may need an Alfuzosinehydrochloride retard PCH dose adjustment or special tests:

prostate cancer;

liver disease;

kidney disease;

a personal or family history of Long QT syndrome;

angina (chest pain);

coronary artery disease (hardened arteries);

a history of low blood pressure (even when caused by taking medications); or

if you are taking certain medicines to treat HIV or AIDS.

Alfuzosinehydrochloride retard PCH can affect your pupils during cataract surgery. Tell your eye surgeon ahead of time that you are using this medication. Do not stop using Alfuzosinehydrochloride retard PCH before surgery unless your surgeon tells you to.

Although this medication is not for use in women, Alfuzosinehydrochloride retard PCH is not expected to harm an unborn baby. If you are a woman using this medication, tell your doctor if you are pregnant or breast-feeding. Alfuzosinehydrochloride retard PCH is not for use in children.

Important safety information: 

Alfuzosinehydrochloride retard PCH may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

To prevent dizziness, avoid standing for long periods of time or becoming overheated during exercise and in hot weather.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall. Drinking alcohol can increase certain side effects of Alfuzosinehydrochloride retard PCH.

Many drugs can interact with Alfuzosinehydrochloride retard PCH. Below is just a partial list. Tell your doctor if you are using:

atenolol (Tenormin);

arsenic trioxide (Trisenox);

cimetidine (Tagamet);

conivaptan (Vaprisol);

diltiazem (Cardizem CD, Cartia XT, Tiazac);

droperidol (Inapsine);

enoxacin (Penetrex);

imatinib (Gleevec);

isoniazid (for treating tuberculosis);

an antibiotic such as clarithromycin (Biaxin), dalfopristin/quinupristin (Synercid), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin), levofloxacin (Levaquin), moxifloxacin (Avelox), pentamidine (NebuPent, Pentam); or telithromycin (Ketek);

an antidepressant such as amitriptylline (Elavil, Vanatrip), clomipramine (Anafranil), desipramine (Norpramin), or nefazodone;

an antifungal medication such as clotrimazole (Mycelex Troche) o voriconazole (Vfend);

anti-malaria medications such as chloroquine (Arelan) or mefloquine (Lariam);

a nitrate heart medication, such as nitroglycerin (Nitrostat, Nitrolingual, Nitro-Dur, Nitro-Bid, and others), isosorbide dinitrate (Dilatrate-SR, Isordil, Sorbitrate), or isosorbide mononitrate (Imdur, ISMO, Monoket);

heart or blood pressure medication such as diltiazem (Cartia, Cardizem), felodipine (Plendil), nifedipine (Nifedical, Procardia), verapamil (Calan, Covera, Isoptin, Verelan), and others;

heart rhythm medicine such as amiodarone (Cordarone, Pacerone), dofetilide (Tikosyn), disopyramide (Norpace), ibutilide (Corvert), procainamide (Pronestyl), propafenone (Rythmol), quinidine (Quin-G), or sotalol (Betapace);

HIV/AIDS medicine such as atazanavir (Reyataz), delavirdine (Rescriptor), fosamprenavir (Lexiva), indinavir (Crixivan), nelfinavir (Viracept), saquinavir (Invirase), or ritonavir (Norvir);

medicine to prevent or treat nausea and vomiting, such as dolasetron (Anzemet) or ondansetron (Zofran);

medicines to treat psychiatric disorders, such as chlorpromazine (Thorazine), clozapine (FazaClo, Clozaril), haloperidol (Haldol), pimozide (Orap), thioridazine (Mellaril), or ziprasidone (Geodon);

migraine headache medicine such as sumatriptan (Imitrex) or zolmitriptan (Zomig); or

narcotic medication such as methadone (Dolophine, Methadose).

This list is not complete and there are many other drugs that can interact with Alfuzosinehydrochloride retard PCH. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.

SIDE EFFECTS

Get emergency medical help if you have any of these signs of an allergic reaction to Alfuzosinehydrochloride retard PCH: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using Alfuzosinehydrochloride retard PCH and call your doctor at once if you have a serious side effect such as:

new or worsening chest pain;

nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);

feeling like you might pass out; or

penis erection that is painful or lasts 4 hours or longer.

Less serious Alfuzosinehydrochloride retard PCH side effects may include:

mild dizziness;

headache;

tired feeling; or

cold symptoms such as stuffy nose, sneezing, sore throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.


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Es ist wichtig, den Sicherheitsempfehlungen zu folgen und die Gegenanzeigen, Warnhinweise und Vorsichtsmaßnahmen zu berücksichtigen, damit sich das Risiko schlimmer Reaktionen und Nebenwirkungen reduziert. Es kommt leider bei Patienten mit Überempfindlichkeit gegen einigen Komponenten des Arzneimittels zu leichten bis schweren nachteiligen Reaktionen, die im Text unten zu finden sind. Um das Risiko ernster Folgen auszuschalten, wenden Sie sich an Ihren Therapeuten oder an einen Online-Facharzt. Man benötigt dringende medizinische Hilfe, wenn folgende Nebenwirkungen zu bemerken sind:

Rare

  • Chest pain
  • chills
  • cold sweats
  • confusion
  • dizziness, faintness, or lightheadedness when getting up from a lying or sitting position
  • fainting
  • fast, pounding, or irregular heartbeat or pulse
  • painful or prolonged erection of the penis
  • Rash

More Common

  • Dizziness

Less Common

  • Abdominal or stomach pain
  • acid or sour stomach
  • belching
  • body aches or pain
  • congestion
  • cough
  • cough producing mucus
  • decreased interest in sexual intercourse
  • difficulty breathing
  • difficulty having a bowel movement (stool)
  • dryness or soreness of the throat
  • ear congestion
  • fever
  • headache
  • heartburn
  • hoarseness
  • inability to have or keep an erection
  • indigestion
  • loss in sexual ability, desire, drive, or performance
  • loss of voice
  • nasal congestion
  • pain
  • pain or tenderness around the eyes and cheekbones
  • sneezing
  • sore throat
  • stomach discomfort, upset, or pain
  • stuffy or runny nose
  • tender, swollen glands in the neck
  • tightness in the chest
  • trouble with swallowing
  • unusual tiredness or weakness
  • voice changes
  • wheezing

Incidence Not Known

  • Arm, back, or jaw pain
  • chest discomfort
  • chest tightness or heaviness
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • nausea
  • shortness of breath
  • sweating
  • swelling
  • Diarrhea
  • feeling of warmth
  • hives or welts
  • itching skin
  • redness of the skin
  • redness of the face, neck, arms, and occasionally, upper chest
Type Small Molecule
Accession Number DB00346  (APRD00490)
Groups Approved, Investigational
Synonyms
  • (±)-N-[3-[(4-amino-6,7-dimethoxy-2-quinazolinyl)methylamino]propyl]tetrahydro-2-furamide
  • Alfuzosin
  • Alfuzosina
  • Alfuzosine
  • Alfuzosinum
  • N-[3-[(4-amino-6,7-dimethoxy-quinazolin-2-yl)- methyl-amino]propyl] tetrahydrofuran- 2-carboxamide
UNII 90347YTW5F
CAS number 81403-80-7
Weight Average: 389.4488
Monoisotopic: 389.206304377
Chemical Formula C19H27N5O4
InChI
InChI=1S/C19H27N5O4/c1-24(8-5-7-21-18(25)14-6-4-9-28-14)19-22-13-11-16(27-3)15(26-2)10-12(13)17(20)23-19/h10-11,14H,4-9H2,1-3H3,(H,21,25)(H2,20,22,23)
IUPAC Name
N-{3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)(methyl)amino]propyl}oxolane-2-carboxamide
Protein binding

82%-90%

Toxicity

Side effects are dizziness (due to postural hypotension), upper respiratory tract infection, headache, and fatigue.

Half life

10 hours

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